Associate alzheimer’s disease with a diet high in carbohydrates

Researchers from the School of Public Health at Imperial College London hasn followed the progress of five thousand people for ten years and concluded that those who have the blood sugar high with a declining at a faster rate of cognitive skills, the margin of which the level of sugar in blood to do it or not technically diabetic. The study, recently published in Diabetologia, is just the latest of a series of works that point in the same direction.

In 2012, the neuropatóloga of Brown University Suzanne de la Monte applied to the brain of some mice with a drug that interfered with the normal functioning of the insulin. The result was devastating: not only ceased to be able to circulate through the proverbial maze, but to make the autopsy noted that the brain had damage classics of alzheimer’s disease. It was this researcher who, in the view of these findings, they renamed the alzheimer’s as diabetes type 3.

The same year, Rosebud Roberts, professor of Epidemiology and Neurology at the Mayo Clinic, published a study that divided approximately one thousand people in four different groups depending on the volume of carbohydrates in your diet. Those who belonged to the group with the highest consumption had a 80% more likely to develop mild cognitive impairment –a first step in the direction of senile dementia– that those who were in the group of lower consumption.

The mechanism by which this occurs is not clear, but according to Melissa Schilling, professor at New York University, the reason may be that the enzyme responsible for destroying the insulin also is the one that destroys the plaques beta-amyloid whose accumulation in the brain causes dementia. And everything that causes problems in the proper functioning of insulin may make these enzymes fail to effectively do their job in the brain.